The most common and most likely answer to this crossword clue is the 3 plus 11 letter word JOB DESCRIPTION
I've seen this crossword clue in The Times
J
O
B
D
E
S
C
R
I
P
T
I
O
N
More clues leading to the result JOB DESCRIPTION
- Book with strange predictions on what’s to be done
- Outline of duties for which patient may be employed?
- Patient fellow’s account, list of duties, tasks etc
- Patient perhaps getting list of tasks
- What you must do is drop object in liquid
- Explanation of position‘s requirements for patient?
- Outline of a post
- Prophetic part of CV?
Buddy explains!

The straight part
We know that "what’s to be done" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case what’s to be done = job description.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.