Cryptic crossword clue
Boss, cunning, securing promissory note with due diligence 10

The most common and most likely answer to this crossword clue is the 10 letter word STUDIOUSLY

I've seen this crossword clue in The Daily Telegraph
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Buddy explains!

The straight part
We know that "with due diligence" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case with due diligence = studiously.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does STUDIOUSLY mean?

STUDIOUSLY adverb
  1. In a studious manner.

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