Cryptic crossword clue
Boxer interrupts breaks, those that are practical 8

The most common and most likely answer to this crossword clue is the 8 letter word REALISTS

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Buddy explains!

The straight part
We know that "those that are practical" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case those that are practical = realists.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does REALISTS mean?

REALISTS noun
  1. An advocate of realism; one who believes that matter, objects etc. have real existence beyond our perception of them.
  2. One who believes in seeing things the way they really are, as opposed to how they would like them to be.
  3. An adherent of the realism movement; an artist who seeks to portray real everyday life accurately.

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