Cryptic crossword clue
Brace used to help the spine, when oxygen is in short supply 8

The most common and most likely answer to this crossword clue is the 8 letter word ORTHOSIS

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "Brace used to help the spine" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case brace used to help the spine = orthosis.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ORTHOSIS mean?

ORTHOSIS noun
  1. A type of brace which either prevents or assists movement of a limb or the spine.

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