Cryptic crossword clue
Break down ‘alternative facts’ de nos jours, we hear 4

The most common and most likely answer to this crossword clue is the 4 letter word LYSE

L
Y
S
E

Buddy explains!

The straight part
We know that "Break down" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case break down = lyse.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does LYSE mean?

LYSE verb
  1. To burst or cut a cell or cell structure; to induce lysis.
  2. To break down molecularly into smaller molecules; to induce lysis.

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