The most common and most likely answer to this crossword clue is the 10 letter word IMPATIENCE
I've seen this crossword clue in Financial Times
I
M
P
A
T
I
E
N
C
E
More clues leading to the result IMPATIENCE
- Being short of one million on card game
- Bride at Savoy announcing herself in agitation?
- Intolerance of empty idiom applied to card game
- Animal’s heart associated with card game – not a virtue!
- Male in one card game showing restlessness
- Arrange a nice time without pressure? Job didn’t suffer from it
- Restlessness evident in self-identification of G&S character
- Purpose initially lacking before game — producing restlessness
- Eagerness to get at mince pie’s deplorable
- 999p ÷ @1 causing irritability?
Buddy explains!

The straight part
We know that "agitation?" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case agitation? = impatience.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does IMPATIENCE mean?
IMPATIENCE noun- The quality of being impatient; lacking patience; restlessness and intolerance of delays; anxiety and eagerness, especially to begin something.