Cryptic crossword clue
Brighten up run-down university, the one I went to 8

The most common and most likely answer to this crossword clue is the 8 letter word ILLUMINE

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "Brighten up" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case brighten up = illumine.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ILLUMINE mean?

ILLUMINE verb
  1. To illuminate.
  2. To light up.

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