Cryptic crossword clue
Brings solace when upset, very ill at ease! 10

The most common and most likely answer to this crossword clue is the 10 letter word ALLEVIATES

I've seen this crossword clue in The Times
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The straight part
We know that "Brings solace" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case brings solace = alleviates.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ALLEVIATES mean?

ALLEVIATES verb
  1. To make less severe, as a pain or difficulty.

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