The most common and most likely answer to this crossword clue is the 10 letter word CIGARETTES
I've seen this crossword clue in The Daily Telegraph
C
I
G
A
R
E
T
T
E
S
More clues leading to the result CIGARETTES
- Charlie and I get a rest arranged — we’re puffed!
- Matilda’s magic not starting, backfires and smokes
- Tabs kept by spooks conclusively spying on revolutionary individual like me
- They are made ready to meet their match
- Broken grate included in quotes smokes
- Great city almost destroyed by drug, surely top killers, perhaps
- Quotes about great plastic products that cause serious damage
Buddy explains!

The straight part
We know that "smokes" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case smokes = cigarettes.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does CIGARETTES mean?
CIGARETTES noun- Tobacco or other substances, in a thin roll wrapped with paper, intended to be smoked.
- To give someone a cigarette, and/or to light one for them.