Cryptic crossword clue
Brute causes a disturbance internally 6

The most common and most likely answer to this crossword clue is the 6 letter word SADIST

I've seen this crossword clue in The Guardian
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The straight part
We know that "Brute" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case brute = sadist.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SADIST mean?

SADIST noun
  1. One who derives pleasure through cruelty or pain to others.

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