The most common and most likely answer to this crossword clue is the 7 letter word MYRIADS
I've seen this crossword clue in The Guardian
M
Y
R
I
A
D
S
Buddy explains!
The straight part
We know that "lots" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lots = myriads.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does MYRIADS mean?
MYRIADS noun- Ten thousand; 10,000
- A countless number or multitude (of specified things)