Cryptic crossword clue
Burly bouncer primarily manages safe area 10

The most common and most likely answer to this crossword clue is the 10 letter word STRONGROOM

I've seen this crossword clue in Financial Times
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Buddy explains!

The straight part
We know that "safe area" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case safe area = strongroom.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does STRONGROOM mean?

STRONGROOM noun
  1. A strongly built room or vault where valuables may be safely stored.

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