The most common and most likely answer to this crossword clue is the 10 letter word INVINCIBLE
I've seen this crossword clue in The Guardian
I
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Buddy explains!

The straight part
We know that "impossible to conquer" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case impossible to conquer = invincible.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does INVINCIBLE mean?
INVINCIBLE noun- Someone or something that cannot be defeated, destroyed or killed.
- Impossible to defeat, destroy or kill; too powerful to be defeated or overcome.