Cryptic crossword clue
Cad afflicted with ruin inclined to fly off the handle 7

The most common and most likely answer to this crossword clue is the 7 letter word IRACUND

I
R
A
C
U
N
D


Buddy explains!

The straight part
We know that "inclined to fly off the handle" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case inclined to fly off the handle = iracund.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does IRACUND mean?

IRACUND adjective
  1. Angry; irritable

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