Cryptic crossword clue
Caesar, perhaps, in his day and age had one with Antony … 8

The most common and most likely answer to this crossword clue is the 8 letter word BROMANCE

I've seen this crossword clue in The Guardian
B
R
O
M
A
N
C
E


Buddy explains!

The straight part
We know that "had one with Antony" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case had one with antony = bromance.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BROMANCE mean?

BROMANCE noun
  1. A close but non-sexual relationship between men.

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