Cryptic crossword clue
Call home in a dreadfully depressed state 11

The most common and most likely answer to this crossword clue is the 11 letter word MELANCHOLIA

I've seen this crossword clue in The Sunday Telegraph
M
E
L
A
N
C
H
O
L
I
A

Buddy explains!

The straight part
We know that "depressed state" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case depressed state = melancholia.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

Crossword Answer definitions

MELANCHOLIA noun
  1. Deep sadness or gloom; melancholy.
  2. Clinical depression, characterised by irrational fears, guilt and apathy.

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