Cryptic crossword clue
Call on me first, in relation to treatment 8

The most common and most likely answer to this crossword clue is the 8 letter word REMEDIAL

I've seen this crossword clue in The Sunday Telegraph
R
E
M
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D
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A
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Buddy explains!

The straight part
We know that "relation to treatment" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case relation to treatment = remedial.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does REMEDIAL mean?

REMEDIAL adjective
  1. Curative; providing a remedy
  2. Intended to correct or improve deficient skills in some subject

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