The most common and most likely answer to this crossword clue is the 9 letter word PHEROMONE
I've seen this crossword clue in The Daily Telegraph
P
H
E
R
O
M
O
N
E
More clues leading to the result PHEROMONE
- Chemical secretion more flexible in mobile device?
- Star with external power and endless cash, the means to attract a mate?
- Quiet champion attracting maiden, individual that may send out bodily signal
- Handheld device with withdrawn extra installed that subliminally affects behaviour?
- Call to import more retrograde chemical substance
- Secreted chemical: call to inject extra rejected
- Secreting this, perhaps more hope to enthral women ultimately
- Her poem on change may be arousing for others
Buddy explains!

The straight part
We know that "chemical substance" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case chemical substance = pheromone.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does PHEROMONE mean?
PHEROMONE noun- A chemical secreted by an animal, especially an insect, that affects the development or behavior of other members of the same species, functioning often as a means of attracting a member of the opposite sex.