The most common and most likely answer to this crossword clue is the 6 letter word METIER
M
E
T
I
E
R
More clues leading to the result METIER
- Strong suit of this writer, wild beast with no heart
- This trade would become more interesting if American were admitted
- Contest in water off France is something I’m good at
- Job of the compiler on line
- One’s engrossed by instrument, it’s one’s thing
- Speciality, level beyond me
- More interesting to get rid of a line of business
- Note grade and speciality
- Calling on couple, directed the wrong way
Buddy explains!

The straight part
We know that "Calling" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case calling = metier.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does METIER mean?
METIER noun- Any activity that is pursued as a trade or profession; a calling.
- An activity to which a person is particularly suited; a forte.
- An outstanding or beneficial feature.