Cryptic crossword clue
Callixenus comprehends his limits age wise 15

The most common and most likely answer to this crossword clue is the 15 letter word QUINQUAGENARIAN

I've seen this crossword clue in The Times
Q
U
I
N
Q
U
A
G
E
N
A
R
I
A
N

Buddy explains!

The straight part
We know that "his" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case his = quinquagenarian.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does QUINQUAGENARIAN mean?

QUINQUAGENARIAN noun
  1. One who is between the age of 50 and 59, inclusive.
QUINQUAGENARIAN adjective
  1. Being between the age of 50 and 59, inclusive.
  2. Of or relating to a quinquagenarian.

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