Cryptic crossword clue
Callous as Doris would become after Rex left 9

The most common and most likely answer to this crossword clue is the 9 letter word HEARTLESS

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "Callous" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case callous = heartless.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HEARTLESS mean?

HEARTLESS adjective
  1. Without courage; fearful, cowardly.
  2. Listless, unenthusiastic.
  3. Without a physical heart.
  4. Without feeling, emotion, or concern for others; uncaring.

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