The most common and most likely answer to this crossword clue is the 4 letter word TINY
I've seen this crossword clue in The Times
T
I
N
Y
More clues leading to the result TINY
- Can baby finally wee?
- Very little can remove point of rising from yeast
- Rebellion? Show hesitation, deposing leading pair
- Small can at back of pantry
- Small-scale revolt ousting character in Athens
- Asian joint, reportedly very cramped
- Very little money end of January
- Minute semi-desert’s abandoned fate
- Minute can start to yawn
- Remove centre of tip any minute
Buddy explains!

The straight part
We know that "wee" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case wee = tiny.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does TINY mean?
TINY noun- A small child; an infant.
- Anything very small.
- Very small.