Cryptic crossword clue
Can I return? First, run away from helping Trigger 10

The most common and most likely answer to this crossword clue is the 10 letter word INITIATION

I've seen this crossword clue in The Guardian
I
N
I
T
I
A
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N

Buddy explains!

The straight part
We know that "Trigger" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case trigger = initiation.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INITIATION mean?

INITIATION noun
  1. The act of initiating, or the process of being initiated or introduced
  2. The form or ceremony by which a person is introduced into any society; mode of entrance into an organized body; especially, the rite of admission into a secret society or order.
  3. The first step of transcription or of transduction.

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