The most common and most likely answer to this crossword clue is the 6 letter word IGUANA
I've seen this crossword clue in The Daily Telegraph
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More clues leading to the result IGUANA
- Reptile disfiguring canal’s central parts
- Crested lizard one year vanishing from country
- Reptile seen in Antigua naturally?
- Reptile, one to the fore in S American region
- Refresh again after plugging in universal monitor
- Lizards wandering in Nicaragua avoiding vehicle
- Lizard droppings mostly found in Iowa
- Reptile of Antiguan antiquity
- Lizard, one climbing in South American region
- Creature‘s droppings mostly deposited in middle of aviary
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does IGUANA mean?
IGUANA noun- A green iguana (Iguana iguana), a large tropical American lizard often kept as a pet
- In zoology, any member of the genus Iguana
- Colloquially, in America and the Pacific, any of several members of the lizard family Iguanidae.
- Colloquially, in Africa, any large member of the genus Varanus, especially the aquatic Nile monitor -- see leguan
- Colloquially, in Australia, any member of the genus Varanus -- see goanna