Cryptic crossword clue
Car takes wrong route crossing river 6

The most common and most likely answer to this crossword clue is the 6 letter word TOURER

I've seen this crossword clue in The Daily Telegraph
T
O
U
R
E
R

Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does TOURER mean?

TOURER noun
  1. An open-top or soft-top motor car suitable for touring.
  2. A touring bicycle.

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