Cryptic crossword clue
Care of Bond’s boss, hands Bond opening 12

The most common and most likely answer to this crossword clue is the 12 letter word COMMENCEMENT

I've seen this crossword clue in The Daily Telegraph
C
O
M
M
E
N
C
E
M
E
N
T


Buddy explains!

The straight part
We know that "opening" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case opening = commencement.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does COMMENCEMENT mean?

COMMENCEMENT noun
  1. The first existence of anything; act or fact of commencing
  2. The day when degrees are conferred by colleges and universities upon students and others.
  3. A graduation ceremony, from a school, college or university.

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