Cryptic crossword clue
Career of mostly courteous Independent and Conservative ministers at the end 8

The most common and most likely answer to this crossword clue is the 8 letter word POLITICS

I've seen this crossword clue in The Daily Telegraph
P
O
L
I
T
I
C
S

Buddy explains!

The straight part
We know that "Career" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case career = politics.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does POLITICS mean?

POLITICS verb
  1. To engage in political activity; politick.
POLITICS noun
  1. A methodology and activities associated with running a government, an organization, or a movement.
  2. The profession of conducting political affairs.
  3. (plural) One's political stands and opinions.
  4. Political maneuvers or diplomacy between people, groups, or organizations, especially involving power, influence or conflict.
  5. (singular) Real-world beliefs and social issues irrelevant to the topic at hand.

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