Cryptic crossword clue
Cartoonist, maybe, about to get prize

The most common and most likely answer to this crossword clue is the 6 letter word REWARD

I've seen this crossword clue in Independent
R
E
W
A
R
D


Buddy explains!

The straight part
We know that "prize" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case prize = reward.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does REWARD mean?

REWARD noun
  1. Something of value given in return for an act.
  2. A prize promised for a certain deed or catch
  3. The result of an action, whether good or bad.
REWARD verb
  1. To give a reward to or for.
  2. To recompense.
  3. To give (something) as a reward.

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