Cryptic crossword clue
Case of painful fever and small afflictions 7

The most common and most likely answer to this crossword clue is the 7 letter word PLAGUES

I've seen this crossword clue in The Daily Telegraph
P
L
A
G
U
E
S

Buddy explains!

The straight part
We know that "afflictions" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case afflictions = plagues.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PLAGUES mean?

PLAGUES noun
  1. (often used with the, sometimes capitalized: the Plague) The bubonic plague, the pestilent disease caused by the virulent bacterium Yersinia pestis.
  2. An epidemic or pandemic caused by any pestilence, but specifically by the above disease.
  3. A widespread affliction, calamity or destructive influx, especially when seen as divine retribution.
  4. A grave nuisance, whatever greatly irritates.
  5. Collective noun for common grackles
PLAGUES verb
  1. To harass, pester or annoy someone persistently or incessantly.
  2. To afflict with a disease or other calamity.

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