Cryptic crossword clue
Cat beetled off before one’s very eyes 10

The most common and most likely answer to this crossword clue is the 10 letter word DETECTABLE

I've seen this crossword clue in The Guardian
D
E
T
E
C
T
A
B
L
E

Buddy explains!

The straight part
We know that "before one’s very eyes" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case before one’s very eyes = detectable.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DETECTABLE mean?

DETECTABLE adjective
  1. That which can be detected, noticeable.

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