Cryptic crossword clue
Cat kept by defendant very much at home 10

The most common and most likely answer to this crossword clue is the 10 letter word ACCUSTOMED

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "very much at home" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case very much at home = accustomed.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ACCUSTOMED mean?

ACCUSTOMED adjective
  1. (of a person) Familiar with something through repeated experience; adapted to existing conditions.
  2. (of a thing, condition, activity, etc.) Familiar through use; usual; customary.
  3. Frequented by customers.

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