Cryptic crossword clue
Catharine’s chewed about five hundred Spanish flies 11

The most common and most likely answer to this crossword clue is the 11 letter word CANTHARIDES

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CANTHARIDES mean?

CANTHARIDES noun
  1. Spanish fly Lytta vesicatoria (syn. Cantharis vesicatoria).
  2. Spanish fly; a vesicant extracted from the beetle, popularly held to have aphrodisiac properties.

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