The most common and most likely answer to this crossword clue is the 8 letter word AGGRIEVE
I've seen this crossword clue in The Times
A
G
G
R
I
E
V
E
More clues leading to the result AGGRIEVE
- Trouble giver sadly seen in maturity
- Cause to resent a confused veggie eating rook
- Give gear mistakenly, causing distress
- Trouble with endless Viagra, get off tablet
- Cause sadness by putting ricotta topping into a veggie dish …
- Silver rig-out on girl is wrong
- Injure German through a piece of armour by the sound of it
- Raging about having snubbed new first lady in distress
- Distress for Rhode Island woman under gag order
- I gave Reg fluid for pain
Buddy explains!

The straight part
We know that "Cause to resent" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case cause to resent = aggrieve.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.