Cryptic crossword clue
Cavalier villain could be a nurse 5-3-4

The most common and most likely answer to this crossword clue is the 14 letter word DEVIL-MAY-CARE

I've seen this crossword clue in Financial Times
D
E
V
I
L
-
M
A
Y
-
C
A
R
E

Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DEVIL-MAY-CARE mean?

DEVIL-MAY-CARE adjective
  1. Carefree, reckless, irresponsible.

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