The most common and most likely answer to this crossword clue is the 5 letter word SUCRE
S
U
C
R
E
Buddy explains!
The straight part
We know that "somewhere in the Andes" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case somewhere in the andes = sucre.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SUCRE mean?
SUCRE noun- The former currency of Ecuador, divided into 100 centavos.