Cryptic crossword clue
Certain to get drunk on Adam’s ale 10

The most common and most likely answer to this crossword clue is the 10 letter word WATERTIGHT

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "Certain" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case certain = watertight.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does WATERTIGHT mean?

WATERTIGHT adjective
  1. So tightly made that water cannot enter or escape.
  2. So devised or planned as to be impossible to defeat, evade or nullify.

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