Cryptic crossword clue
Change character of versatile Durante by removal of all but tip of schnozzle 8

The most common and most likely answer to this crossword clue is the 8 letter word DENATURE

D
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DENATURE mean?

DENATURE verb
  1. To take away a natural characteristic or inherent property of (a thing or a person).
  2. To add something to (alcohol) that makes it unsuitable for consumption but leaves it suitable for other purposes.
  3. To alter its original form or state, especially of a protein, by heat, acidity etc.
  4. To combine fissionable material with nonfissionable material in order to prevent its use in an atomic weapon.

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