Cryptic crossword clue
Change now due with city and across region 10

The most common and most likely answer to this crossword clue is the 10 letter word COUNTYWIDE

I've seen this crossword clue in Financial Times
C
O
U
N
T
Y
W
I
D
E

Buddy explains!

The straight part
We know that "across region" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case across region = countywide.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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