Cryptic crossword clue
Charge rascal after commencement of prescription 6

The most common and most likely answer to this crossword clue is the 6 letter word IMPOST

I
M
P
O
S
T

Buddy explains!

The straight part
We know that "Charge" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case charge = impost.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does IMPOST mean?

IMPOST noun
  1. A tax, tariff or duty that is imposed, especially on merchandise.
  2. The weight that must be carried by a horse in a race, the handicap.
IMPOST noun
  1. The top part of a column, pillar, pier, wall, etc. that supports an arch.

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