Cryptic crossword clue
Charge to protect a gun-running fugitive 8

The most common and most likely answer to this crossword clue is the 8 letter word RUNAGATE

R
U
N
A
G
A
T
E

Buddy explains!

The straight part
We know that "fugitive" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case fugitive = runagate.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RUNAGATE mean?

RUNAGATE noun
  1. A deserter, renegade or apostate.
  2. A fugitive; a runaway.

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