The most common and most likely answer to this crossword clue is the 8 letter word ISTANBUL
I
S
T
A
N
B
U
L
More clues leading to the result ISTANBUL
- One sultan resolved to capture British port
- City in which Cyclops has nuts ‘lab-modified’
- I almost tolerate most of nonsense somewhere in Turkey
- Saint high on life, ultimately blessed, starts back in big city
- Originally Byzantium, a sunlit resort?
- Saint sent abridged papal document to Byzantium
- City somewhere between Uzbekistan and Bulgaria
- Fifty ejected from Tallin bus travelling in foreign capital
- Afghanistan bullies besieging city
- Joining EU may be unsuitable
Buddy explains!
The straight part
We know that "city" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case city = istanbul.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.