The most common and most likely answer to this crossword clue is the 4 letter word DUST
I've seen this crossword clue in Financial Times
D
U
S
T
More clues leading to the result DUST
- Remains of the French Saint
- Springfield was 80% clean
- Little bits of dirt under sofas, typically
- Clean American shakes blankets
- Quantity of dirt suddenly swirling?
- Hoffman not at home to clean
- Ashes of French saint
- What may be swept under the carpet at uni results in quarrel
- Dirty stuff produced by some industries
- Aggressive behaviour remains high?
Buddy explains!

The straight part
We know that "Clean" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case clean = dust.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DUST mean?
DUST noun- Fine particles
- The act of cleaning by dusting.
- The earth, as the resting place of the dead.
- The earthy remains of bodies once alive; the remains of the human body.
- Something worthless.
- A low or mean condition.
- Cash; money (in reference to gold dust).
- A disturbance or uproar.
- A totally disconnected set of points with a fractal structure.
- To remove dust from.
- To remove dust; to clean by removing dust.
- Of a bird, to cover itself in sand or dry, dusty earth.
- To spray or cover something with fine powder or liquid.
- To leave; to rush off.
- To reduce to a fine powder; to levigate.
- To kill or severely disable.