Cryptic crossword clue
Clear a chessboard, taking great pains? No, little ones 8

The most common and most likely answer to this crossword clue is the 8 letter word EARACHES

I've seen this crossword clue in The Daily Telegraph
E
A
R
A
C
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E
S

Buddy explains!

The straight part
We know that "great pains? No, little ones" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case great pains? no, little ones = earaches.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EARACHES mean?

EARACHES noun
  1. A pain in the middle or inner ear.

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