The most common and most likely answer to this crossword clue is the 12 letter word HALF-CENTURY
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Buddy explains!
The straight part
We know that "50" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case 50 = half-century.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does HALF-CENTURY mean?
HALF-CENTURY noun- A period of fifty years, half of a century.
- A score of 50 runs by a single batsman
- A score of 50 points in a single game.