Cryptic crossword clue
Cold nurses agitated disreputable men 10

The most common and most likely answer to this crossword clue is the 10 letter word SCOUNDRELS

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "disreputable men" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case disreputable men = scoundrels.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SCOUNDRELS mean?

SCOUNDRELS noun
  1. A mean, worthless fellow; a rascal; a villain; a person without honour or virtue.

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