Cryptic crossword clue
Column perhaps about to slam criminal getting life in cell 10

The most common and most likely answer to this crossword clue is the 10 letter word PROTOPLASM

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Buddy explains!

The straight part
We know that "life in cell" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case life in cell = protoplasm.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PROTOPLASM mean?

PROTOPLASM noun
  1. The entire contents of a cell comprising the nucleus and the cytoplasm. It is a semi-fluid, transparent substance which is the living matter of plant and animal cells.

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