Cryptic crossword clue
Coming out for air, regret it’s cooler 12

The most common and most likely answer to this crossword clue is the 12 letter word REFRIGERATOR

I've seen this crossword clue in The Guardian
R
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Buddy explains!

The straight part
We know that "cooler" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case cooler = refrigerator.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does REFRIGERATOR mean?

REFRIGERATOR noun
  1. A household appliance used for keeping food fresh by refrigeration (short form fridge).
  2. One who has a chilling influence.

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