The most common and most likely answer to this crossword clue is the 6 letter word ISAIAH
I've seen this crossword clue in The Guardian
I
S
A
I
A
H
More clues leading to the result ISAIAH
- This writer needs stamina now and then with hard book
- Book this writer has tipped — it's about perfect
- Book one owns about investing capital
- Investment product used by Hitachi regularly yields a profit, we’re told?
- Savings scheme – one that’s good making profit, reportedly
- Commonly told to look up prophet
- Book One has returned with “Excellent” inside
- Book one has returned with excellent contents
- Pronounced views anger Old Testament prophet
- Book is perfect, I see!
Buddy explains!

The straight part
We know that "prophet/prophet" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case prophet/prophet = isaiah.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.