Cryptic crossword clue
Complaint about Iris Murdoch’s last tart 9

The most common and most likely answer to this crossword clue is the 9 letter word ARTHRITIS

I've seen this crossword clue in The Guardian
A
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Buddy explains!

The straight part
We know that "Complaint" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case complaint = arthritis.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ARTHRITIS mean?

ARTHRITIS noun
  1. Inflammation of a joint or joints causing pain and/or disability, swelling and stiffness, and due to various causes such as infection, trauma, degenerative changes or metabolic disorders.

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