Cryptic crossword clue
Contemptible people‘s cruel quips are stopping points 10

The most common and most likely answer to this crossword clue is the 10 letter word PIPSQUEAKS

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "Contemptible people" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case contemptible people = pipsqueaks.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PIPSQUEAKS mean?

PIPSQUEAKS noun
  1. A small and insignificant person.

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